Import tabular data from files to estimate model parameters. Supported file types include Excel®, text, SAS® XPORT, and NONMEM®-formatted files. Visualize and categorize the data in the SimBiology Model Analyzer app or at the command line. Use the time course data of measured drug concentrations to perform noncompartmental analysis (NCA) and calculate PK parameters.
|Convert groupedData object to table|
|Compute noncompartmental analysis (NCA) parameters (requires Statistics and Machine Learning Toolbox)|
|Specify options to calculate noncompartmental analysis (NCA) parameters|
|Import NONMEM-formatted data|
|NONMEM file definition object for sbionmimport|
|Plot data or simulation results in trellis plot|
|Plot simulation results in one figure|
|Plot simulation results in subplots|
Examples and How To
- Calculate NCA Parameters and Fit Model to PK/PD Data Using SimBiology Model Analyzer App
Perform noncompartmental analysis and calibrate model parameters by fitting to experimental PKPD data using nonlinear regression.
- Importing Data
SimBiology lets you import tabular data from external sources programmatically.
- Importing Data — Supported Files and Data Types
SimBiology lets you import external data saved in several file formats, such as Excel files, text files, and NONMEM-formatted files.
- Noncompartmental Analysis
NCA (noncompartmental analysis) lets you calculate pharmacokinetic parameters of a drug without requiring the assumption of a compartmental model.