I have a question about how Simbiology handles volume changes during a simulation. I understand that by assigning ConstantCapacity to false we can allow the capacity of a compartment to change according to some rule; as an example, a tumor compartment that responds to drug treatment. But how does Simbiology handle the concentration of species that reside in this compartment? If tumor is shrinking, the concentration of species within it will increase, which is an artefact.
Any comment would be greatly appreciate.