Large Audio Datastore: MATLAB Workspace

Hi, I have 36 large audio files encoded as Wav: 48kHz / 24 bits.

Each file have approximately 3.6 hours of recording time (or 2Gb size).

Inside each file, I recorded 1000 times the same single musical note played at a acoustic piano, like:

Note - Silence - Note - Silence - Note - Silence.

Now I want to apply some statistic in this audio data store, comparing the signal of each note, but I need sugestions how to prepare the MATLAB workspace well.

1- How to select/import the signal of the "desired note" located inside the 36 large audio files.

2- Is a better solution split each large audio file into small audio files (single note)?

3- I have 32GB of RAM. Could be a solution this? https://www.mathworks.com/help/matlab/datastore.html

How can I proced?

Thank you,