Resultados de
Automating Parameter Identifiability Analysis in SimBiology
Is it possible to develop a MATLAB Live Script that automates a series of SimBiology model fits to obtain likelihood profiles? The goal is to fit a kinetic model to experimental data while systematically fixing the value of one kinetic constant (e.g., k1) and leaving the others unrestricted.
The script would perform the following:
Use a pre-configured SimBiology project where the best fit to the experimental data has already been established (including dependent/independent variables, covariates, the error model, and optimization settings).
Iterate over a defined sequence of fixed values for a chosen parameter.
For each fixed value, run the estimation to optimize the remaining parameters.
Record the resulting Sum of Squared Errors (SSE) for each run.
The final output would be a likelihood profile—a plot of SSE versus the fixed parameter value (e.g., k1)—to assess the practical identifiability of each model parameter.
happy to be here
Excited to link up
Hello everyone , i am excited to learn more!
AI for Engineered Systems
47%
Cloud, Software Factories, & DevOps
0%
Electrification
13%
Autonomous Systems and Robotics
13%
Model-Based Design
7%
Wireless Communications
20%
15 votos
Hi. I'm interested to learn more about MATLAB.
excited to learn more on Mathworks
Looking forward to the Expo!
Registration is now open for MathWorks annual virtual event MATLAB EXPO 2025 on November 12 – 13, 2025!
Register now and start building your customized agenda today!
Explore. Experience. Engage.
Join MATLAB EXPO to connect with MathWorks and industry experts to learn about the latest trends and advancements in engineering and science. You will discover new features and capabilities for MATLAB and Simulink that you can immediately apply to your work.
For some time now, this has been bugging me - so I thought to gather some more feedback/information/opinions on this.
What would you classify Recursion? As a loop or as a vectorized section of code?
For context, this query occured to me while creating Cody problems involving strict (so to speak) vectorization - (Everyone is more than welcome to check my recent Cody questions).
To make problems interesting and/or difficult, I (and other posters) ban functions and functionalities - such as for loops, while loops, if-else statements, arrayfun() and the rest of the fun() family functions. However, some of the solutions including the reference solution I came up with for my latest problem, contained recursion.
I am rather divided on how to categorize it. What do you think?
For the www, uk, and in domains,a generative search answer is available for Help Center searches. Please let us know if you get good or bad results for your searches. Some have pointed out that it is not available in non-english domains. You can switch your country setting to try it out. You can also ask questions in different languages and ask for the response in a different language. I get better results when I ask more specific queries. How is it working for you?
Hello MATLAB Central community,
My name is Yann. And I love MATLAB. I also love Python ... 🐍 (I know, not the place for that).
I recently decided to go down the rabbit hole of AI. So I started benchmarking deep learning frameworks on basic examples. Here is a recording of my experiment:
Happy to engage in the debate. What do you think?
Large Language Models (LLMs) with MATLAB was updated again today to support the newly released OpenAI models GPT-5, GPT-5 mini, GPT-5 nano, GPT-5 chat, o3, and o4-mini. When you create an openAIChat object, set the ModelName name-value argument to "gpt-5", "gpt-5-mini", "gpt-5-nano", "gpt-5-chat-latest", "o4-mini", or "o3".
This is version 4.4.0 of this free MATLAB add-on that lets you interact with LLMs on MATLAB. The release notes are at Release v4.4.0: Support for GPT-5, o3, o4-mini · matlab-deep-learning/llms-with-matlab
Hey cody fellows :-) !
I recently created two problem groups, but as you can see I struggle to set their cover images :
What is weird given :
- I already did it successfully twice in the past for my previous groups ;
- If you take one problem specifically, Problem 60984. Mesh the icosahedron for instance, you can normally see the icon of the cover image in the top right hand corner, can't you ?
- I always manage to set cover images to my contributions (mostly in the filexchange).
I already tried several image formats, included .png 4/3 ratio, but still the cover images don't set.
Could you please help me to correctly set my cover images ?
Thank you.
Nicolas
The Graphics and App Building Blog just launched its first article on R2025a features, authored by Chris Portal, the director of engineering for the MATLAB graphics and app building teams.
Over the next few months, we'll publish a series of articles that showcase our updated graphics system, introduce new tools and features, and provide valuable references enriched by the perspectives of those involved in their development.
To stay updated, you can subscribe to the blog (look for the option in the upper left corner of the blog page). We also encourage you to join the conversation—your comments and questions under each article help shape the discussion and guide future content.
I want to observe the time (Tmax) to reach maximum drug concentration (Cmax) in my model. I have set up the OBSERVABLES as follows (figure1): Cmax = max(Blood.lL15); Tmax_LT = time(Conc_lL15_LT_nm == max(Conc_lL15_LT_nm)); Tmax_Tm = time(Conc_lL15_Tumor_nm == max(Conc_lL15_Tumor_nm)); After running the Sobol indices program for global sensitivity analysis, with inputs being some parameters and their ranges, the output for Cmax works, but there are some prompts, as shown in figure2. Additionally, when outputting Tmax, the program does not run successfully and reports some errors, as shown in figure2. How can I resolve the errors when outputting Tmax?
I like this problem by James and have solved it in several ways. A solution by Natalie impressed me and introduced me to a new function conv2. However, it occured to me that the numerous test for the problem only cover cases of square matrices. My original solutions, and Natalie's, did niot work on rectangular matrices. I have now produced a solution which works on rectangular matrices. Thanks for this thought provoking problem James.
Large Languge model with MATLAB, a free add-on that lets you access LLMs from OpenAI, Azure, amd Ollama (to use local models) on MATLAB, has been updated to support OpenAI GPT-4.1, GPT-4.1 mini, and GPT-4.1 nano.
According to OpenAI, "These models outperform GPT‑4o and GPT‑4o mini across the board, with major gains in coding and instruction following. They also have larger context windows—supporting up to 1 million tokens of context—and are able to better use that context with improved long-context comprehension."
What would you build with the latest update?
Provide insightful answers
9%
Provide label-AI answer
9%
Provide answer by both AI and human
21%
Do not use AI for answers
46%
Give a button "chat with copilot"
10%
use AI to draft better qustions
5%
1561 votos
I have written, tested, and prepared a function with four subsunctions on my computer for solving one of the problems in the list of Cody problems in MathWorks in three days. Today, when I wanted to upload or copy paste the codes of the function and its subfunctions to the specified place of the problem of Cody page, I do not see a place to upload it, and the ability to copy past the codes. The total of the entire codes and their documentations is about 600 lines, which means that I cannot and it is not worth it to retype all of them in the relevent Cody environment after spending a few days. I would appreciate your guidance on how to enter the prepared codes to the desired environment in Cody.
