Bispecific Protein Degrader PK-PD Model for SimBiology

Versión 1.0.2 (161 KB) por Derek Bartlett
SimBiology project file for a published PK-PD model for bispecific protein degraders
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Actualizado 31 may 2023

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The SimBiology model described in the following publication:
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
Please note that some of the included visualizations require the "gridfit" routine written by John D'Errico: Surface Fitting using gridfit (https://www.mathworks.com/matlabcentral/fileexchange/8998-surface-fitting-using-gridfit), MATLAB Central File Exchange.

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Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z

Compatibilidad con la versión de MATLAB
Se creó con R2022a
Compatible con cualquier versión desde R2022a
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Versión Publicado Notas de la versión
1.0.2

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.
1.0.1

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.
1.0.0