matrix size and storage capability

Hello, I would like to perform some computations using MATLAB, these computations will consist in saving some large matrices at the end, so I would like to know how can I avoid having out of memory issue by preconditioning the matrices size at the beginning, i.e if a matrix with size let say 8000 x 8000 will generate out of memory, I could decrease the size before starting the calculations , which means I would like to know if there is a way to define a threshold size that doesn't produce a problem and in the meanwhile be large enough for my computations. Thank you!

[Adam]

[~,memInfo] = memory;
memInfo.PhysicalMemory.Available

is what I tend to use. I decide on a percentage of the available space I am willing to use and then, based on the variables I expect to need to create I work out the size my input can be (e.g. if I'm doing some image processing and I know I will create 3 temporary results and 2 output results I use this to determine an estimate of my maximum memory usage, depending if I can delete the temporary results before getting the output results, etc - i.e. an estimate of what my maximum usage will be as a multiple of the input size)

[Ano]

thank you very much for your reply!