How does SimBiology calculate the "lambda" in NCA?

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Seokuee Kim
Seokuee Kim el 16 de Oct. de 2018
Comentada: Seokuee Kim el 16 de Oct. de 2018
I was wonder that How does SimBiology calculate the "lambda" in NCA?
When I use WinNonlin, I can choice the weighting option in linear regression (ex. unweighted, 1/y, 1/y^2).
Although SimBiology doesn't provide the weighting option, I think that Simbiology uses any one of above.
Thank you.

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Arthur Goldsipe
Arthur Goldsipe el 16 de Oct. de 2018
Hi,
Currently (as of R2018b), SimBiology's NCA uses linear regression with all of the points weighted equally. I'm guessing that's what you would call "unweighted."
-Arthur

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