Arthur Goldsipe
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Capabilities of mass action kinetics
Yes, this is exactly the sort of problem SimBiology is designed for. (I'm one of the developers of this product.) You can build ...
13 días hace | 1
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How to use sundials solvers in threads parpool?
I'm not aware of any way to do this. The only workaround I can think of is to use a process pool instead of a thread pool.
17 días hace | 0
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i have a problem with simbiology
It sounds like you have a bad installation. I suggest trying to reinstall.
26 días hace | 0
integration tolerance has not met
If you can share your model or other reproduction steps, then we can likely offer better advice. In the absence of those details...
29 días hace | 0
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PBPK model construction for radioactive probe drugs
Please read the following other posts to understand the constraints on species units: Can I use "mL/kg" and "mg/kg" for compart...
alrededor de 1 mes hace | 0
SimBiology: 'Integration Tolerance Not Met' error occurs when the dose start time is set later than a fixed value.
The error is due to an inability to solve the equations within the specified error tolerances. Unfortunately, I believe this is ...
alrededor de 1 mes hace | 0
"simulations failed when using the initial values of estimated parameters" with simbiology fitting but no error when using the same parameters/setting for sbiosimulate
It's difficult to diagnose without more information. Can you share your code either here on MATLAB Answers or privately with the...
alrededor de 2 meses hace | 0
Using multiple datasets to fit parameters simultaneously in SimBiology
You first need to decide whether these two concentration profiles should be treated as part of the same experiment/simulation. ...
2 meses hace | 1
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Using multiple datasets to fit parameters simultaneously in SimBiology
SimBiology users typically do this by merging the multiple datasets into a single dataset and fitting them constructing an apprp...
2 meses hace | 0
How to add digestibility in SimBiology Model Builder
I'm not sure what you mean by digestibility. The closest I know of is this SimBiology example, which implements a couple of reac...
2 meses hace | 0
Model reduction of simbiology models
Hi Paulo, The model order reduction functionality that you point to is limited to linear time-invariant systems. Most SimBiolog...
3 meses hace | 0
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How to download old version of toolbox?
I think the versions you are allowed to download depend on your license. If you go to https://www.mathworks.com/downloads/ , the...
3 meses hace | 1
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simFunction and dose Array from an input file
Ok, I think I finally understand what's going on. When you create the SimFunction, you only need to specify one "template" dose...
4 meses hace | 0
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Simbiology Model Analyzer: input error for CMAX and Partial AUC
Hi, This is a bug. The bug is triggered if you try to calculate partial areas and some of the subjects don't have enough measur...
4 meses hace | 1
| aceptada
Jump species quantity then stay constant
I don't yet understand what your goal is. Can you provide more details on what behavior you want? A concrete example illustratin...
6 meses hace | 1
how to understand and set the constant and boundarycondition properties.
If the Constant property of a species is true, then the value of that species cannot change at simulation times > 0. At time = 0...
6 meses hace | 0
Unit conversion in Simbiology model
Hi, I'm a developer on the SimBiology team. I'm not sure I fully understand your question, but I'll try to answer based on my cu...
7 meses hace | 0
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How to find the sensitivity of the model output if it is a variable for repeated assignment?
The solution I generally recommend is to calculate the sensitivities yourself by manualy differentiating the repeated assignment...
7 meses hace | 0
how to handle the error 'Levenberg-Marquardt algorithm the Jacobian at BETA0 is ill-conditioned'?
It's difficult to say exactly what's going on without seeing your model and data. One explanation is that your model is not appr...
8 meses hace | 0
How to write code for repetitive process?
If I understand your question, you're asking how to create an event that fires repeatedly. I'm not sure exactly what kind of rep...
8 meses hace | 0
Investigating the effect of two covariates to an estimated parameter
Yes, you can specify multiple covariates. An example covariate expresssion would be exp(theta_fixed + theta1*covariate1 + theta2...
8 meses hace | 0
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Why are population estimated parameters values the same as individual estimated parameters values?
Without the actual project, it's difficult to say what's going on. So let me offer some potential explanations for what you're s...
8 meses hace | 0
How to simulate a drug concentration-time curve with confidence intervals?
Where did this plot come from? Without more information, we won't be able to say exactly how it was created. However, it looks ...
8 meses hace | 0
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Oral Dose Not Exhibiting Absorption/Bioavailability in Simulation
Copying the answer from the comments: "Just wanted to update that I figured out a solution to the problem! I ended up creating a...
9 meses hace | 0
Simbiology Previous Initial Parameters
The results of a fit only contain the outputs of the fit itself (for example, parameter estimates). If you want to reproduce tho...
10 meses hace | 0
Transfer parameter estimates to model
For item #1, the SimBiologyModelAnalyzer app allows you to create a variant of the parameter estimates (see here for more detail...
10 meses hace | 2
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Encoding conditional assignments in SimBiology
Hi emjey, I see this problem solved in one of two ways: 1) Take advantage of true/false getting converted to 1/0 in mathematic...
10 meses hace | 1
How do I fit multiple curves at once, sharing some fitting parameters and floating others?
Are the 6 different analyte concentrations something you want to specify or estimate? Both of these these are possible in SimBio...
11 meses hace | 1
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Different dilution effect on the kinetics of a time course
Hi Luis, Because you don't use units in your model, SimBiology interprets the reaction rates to have dimensions of amount/time....
11 meses hace | 0
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Question re/ matlab.codetools.requiredFilesAndProducts function.
I'd first check the "Certain" field of the pList output to see if these products have been marked as definitely or just possibly...
11 meses hace | 0
