Can I shift the position of a tile in tiledlayout to be skewed?

Is it possible to get a layout like the picture below using tiledlayout?

For the plots below I've used subplot(3,2,5.5) for the last plot. I would like to use tiledlayout instead, as there I can remove the white space between the plots.

Is there a way to get the following layout and remove rebundant white space between the subplots?

[VBBV]

%if true
  % code
% end
t = tiledlayout(3,2,'TileSpacing','none')

You can also use padding to make the figure layout small as

 % if true
    % code
 % end
t =
tiledlayout(3,2,'Padding','none')

Answer 1

[Matt J]

I think that such a layout violates the definition of "tiled" and therefore will not be possible with tiledlayout, however this File Exchange file,

https://www.mathworks.com/matlabcentral/fileexchange/3696-subaxis-subplot

gives you all the same flexibility as subplot, but in addition allows you to control inter-plot spacing. E.g.,

subaxis(2,2,1,1); plot(1:5)

subaxis(2,2,2,1); plot(1:5)

subaxis(2,2,1.5,2); plot(1:5)

Answer 2

[David Szwer]

The solution is to set up tiledlayout with double the number of rows and columns you need, and create each axes as a 2×2 square.

tiledlayout(6,4, 'TileSpacing','None', 'Padding','None')
% The spacing and padding can be 'Normal', 'Compact' or 'None'.

% Create the first four axes - they go in their default positions.
nexttile([2,2])
nexttile([2,2])
nexttile([2,2])
nexttile([2,2])

% The tiles of tiledlayout are numbered across, then down.  The top-left
% corner of your fifth axes would be tile 17, except that you want it in
% the middle of the row.  So you must set the top-left corner to be in cell
% 18.
nexttile(18,[2,2])

This should give the arrangement you want.