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David
David
Última actividad el 26 de Mzo. de 2024

A bit late. Compliments to Chris for sharing.
Athanasios Paraskevopoulos
Athanasios Paraskevopoulos
Última actividad el 17 de Mzo. de 2024

Athanasios Paraskevopoulos
Athanasios Paraskevopoulos
Última actividad el 14 de Mzo. de 2024

Can you solve it?
Chen Lin
Chen Lin
Última actividad el 10 de Feb. de 2024

Hannah
Hannah
Última actividad el 8 de Feb. de 2024

I have been procrastinating on schoolwork by looking at all the amazing designs created in the last MATLAB Flipbook Mini Hack! They are just amazing. The voting is over but what are y'all's personal favorites? Mine is the flapping butterfly, it is for sure a creation I plan to share with others in the future!
Hi All,
I'm trying to plot my observables in the analyzer and running into far more problems than expected. I have two species in my model that are invovled, blood.Insulin (pM) and blood.Glucose (mM), all I want to do is plot the ratio of these two (blood.Insulin/blood.Glucose (dimensionless)) along with my other species in Model Simulation, to compare it to the same ratio from my data.
First, there doesn't seem to be a way to directly add an observable to the logged states in 'Simulate Model', so I've tried to used 'Calculate Observable' based on the data from my last run (IVGTT.LastRun.results) but it says that units are required when unit conversion is enabled, but it should be dimensionless!
My next idea would be to make a non-constant parameter with a repeated assignment, but I feel like I should be able to do this without resorting to that?
Any help or ideas would be appreciated. Thank you, best regards,
Dan
Mike Croucher
Mike Croucher
Última actividad el 29 de En. de 2024

One of my colleauges, Michio, recently posted an implementation of Pong Wars in MATLAB
Making me wonder about variations. What might the resulting patterns look with differing numbers of balls? Different physics etc?
I based my model construction on this PBPK model: PBPK by Armin Sepp. While this is a very convenient script for building a PBPK two-pore model, it's very incovenient for my application to have the species Units defined in molarity. Is there a convenient way to organically switch this model from molarity to grams (or any weight unit)?
Xiaotong
Xiaotong
Última actividad el 4 de En. de 2024

Hi! I'm new to pk modeling and Matlab. Can someone guide me through how to conduct population pk modeling based on pk parameters from non-human primate studies? Much thanks!!!!
Daniel Bending
Daniel Bending
Última actividad el 15 de Nov. de 2023

The title is resonably non-descript, but I can explain it easily:
Say I have an initial Emax model:
v = emax1*[G]^n1/(ec501^n1+[G]^n1)
And I want to place v inside of a second Emax model:
y = emax2*v^n2/(ex502^n2+v^n2)
Currently, I have the full function of v inside y, twice, it's very long and whilst I only need to get it correct once, for readability in the future I'd rather have it in form #2. I've played around with non-constant parameters but I need the steady state to be v, not the rate rule, and I haven't worked out how to make a parameter shift to a form like v, as an observation might.
Are there any recommended solutions or do I simply need to keep with having v fully expressed in y?
Thank you,
Dan
Daniel Bending
Daniel Bending
Última actividad el 31 de Oct. de 2023

Hi All,
I'm currently attempting to implement a Hodgkin-Huxley-type model of membrane potential, ideally I would like a species that represents the membrane potential as its own distinct entity, so as the reference elsewhere. I've currently established a molarity-based work around but it would be great if I could set the units for the species as millivolt, but that throws an error.
Is there an established way to do this? I imagine I'm not the first person to be trying to model a voltage-gated ion channel!
Thank you for your help.
Image Analyst
Image Analyst
Última actividad el 31 de Oct. de 2023

Just in time for Halloween.
Share your fun photos in the comments!
Daniel Bending
Daniel Bending
Última actividad el 31 de Oct. de 2023

Hello,
I've looked around and I haven't found anything obvious about this, but is it possible to link to species/reactions, graphically, in a non-mass transfer sense? I have areas in my model where it would conceptually make sense to be able to see that species or reactions are linked, but if I link them in the standard way it demands that it be involved in the stoichiometry.
Perhaps some kind of dotted line, or similar?
Thank you, best regards,
Dan
Image Analyst
Image Analyst
Última actividad el 10 de Nov. de 2023

Wait for Walter, the rest of us are mere users.
Image Analyst
Image Analyst
Última actividad el 16 de Oct. de 2023

Image Analyst
Image Analyst
Última actividad el 16 de Oct. de 2023

Image Analyst
Image Analyst
Última actividad el 16 de Oct. de 2023