SimBiology Community

Projects



gPKPDSimToolbox

An app to enable easy use of any SimBiology-built model to execute common PKPD analyses such as simulation, data fitting, population simulation, and NCA. Includes case studies.



QSPToolbox

QSP toolbox is a set of functions, structure array conventions, and class definitions that computationally implement critical elements of QSP workflows in an integrated manner.



Target-Mediated Drug Disposition

Generic Target-Mediated Drug Disposition (TMDD) model that accounts for saturable drug-target binding, as well as target mediated elimination.



Systemic Renin-Angiotensin-System

Model of the systemic Renin-Angiotensin-System (RAS) to investigate the effects of different RAS-modulating therapies.



Physiologically-based pharmacokinetics of trichloroethylene

Physiologically based: Human PBPK model for trichloroethylene (TCE) and its metabolites to assess human health risks associated with low level exposure to TCE.